BiochemistrybioRxivPreprint
The Mammalian Cytosolic Type 2 (R)-β-hydroxybutyrate Dehydrogenase (BDH2) is 4-oxo-L-proline Reductase (EC1.1.1.104)
S. P. Kwiatkowski, M. Bozko, M. Zarod…·J. Drozak
This paper identifies BDH2 as the enzyme responsible for reducing 4-oxo-L-proline to cis-4-hydroxy-L-proline, challenging the previous belief that it produces trans-4-hydroxy-L-proline.