Author

S. P. Leonard

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Approach:genetic perturbation / CRISPR· 2 Organism:Arabidopsis· 1 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1

Frequent Co-Authors

J. E. Barrick· 2 shared A. H. M. Z. Ashraf· 1 shared D. M. Mishler· 1 shared L. G. Miller· 1 shared N. A. Moran· 1 shared P. Geng· 1 shared P. J. Lariviere· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 13 mutual co-author links

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2 shared papersMicrobiology

J. E. Barrick

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2 papers

Recent·Most cited

MicrobiologybioRxivPreprintSep 19, 2023

Single-step genome engineering in the bee gut symbiont Snodgrassella alvi

P. J. Lariviere, A. H. M. Z. Ashraf, S. P. Leonard…·J. E. Barrick

The paper develops a one-step genome editing method for Snodgrassella alvi, enabling gene knockouts and insertions with high accuracy and validation of mutant phenotypes.

DOI 10.1101/2023.09.19.558440

bacteria (other)experimental assay

𝕏 PostBluesky

Evolutionary BiologybioRxivSep 16, 2018

Synthetic genome defenses against selfish DNA elements stabilize engineered bacteria against evolutionary failure

P. Geng, S. P. Leonard, D. M. Mishler, J. E. Barrick

This paper develops a CRISPR-based system to silence transposons in bacteria, improving genome stability and reducing mutation rates in engineered cells.

DOI 10.1021/acssynbio.8b00426

E. coliArabidopsis

𝕏 PostBluesky