Author

S. Panjikar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 5

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:protein folding & dynamics· 3 Assay:protein structure· 3 Organism:Arabidopsis· 2 Research Focus:drug response / drug discovery· 2 Organism:bacteria (other)· 1 Approach:biophysical modeling· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

M. D. Hulett· 2 shared A. Barrow· 1 shared A. Gendall· 1 shared A. R. Gendall· 1 shared A. Silva· 1 shared A. T. Smith· 1 shared A. van Oijen· 1 shared B. H. A. Rehm· 1 shared

Activity by Year

2020-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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2 shared papersBiochemistry

M. D. Hulett

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

The role of auxiliary domains in modulating CHD4 activity suggests mechanistic commonality between enzyme families

Y. Zhong, H. Moghaddas Sani, B. Paudel, J. Low, A. Silva, S. Mueller, C. Deshpande, S. Panjikar, X. Reid, M. Bedward, A. van Oijen, J. Mackay

The paper investigates how auxiliary domains in CHD4 modulate its activity, revealing common regulatory mechanisms across chromatin remodelling enzyme families.

bioRxiv · Jun 13, 2022 · PreprintBiochemistry

Phenol Sensing in Nature Modulated via a Conformational Switch Governed by Dynamic Allostery

J. Singh, M. Sahil, S. Ray, C. Dcosta, S. Panjikar, G. Krishnamoorthy, J. Mondal, R. Anand

The paper shows that MopR, an NtrC protein, uses dynamic allostery to sense phenol, altering its conformation and ATPase activity, with implications for evolutionary conservation.

bioRxiv · May 18, 2022Biochemistry

From bacteria to plants: a repurposing strategy in the pursuit for novel herbicides

E. Mackie, A. Barrow, M.-C. Giel, M. D. Hulett, A. Gendall, S. Panjikar, T. Soares da Costa

This study repurposes a failed antibiotic into a herbicide by targeting plant DHDPR, showing efficacy against weeds and no toxicity to human cells.

bioRxiv · Feb 20, 2022 · PreprintBiochemistry

Towards Novel Herbicide Modes of Action by Inhibiting Lysine Biosynthesis in Plants

T. P. Soares da Costa, C. J. Hall, S. Panjikar, J. A. Wyllie, R. M. Christoff, M. D. Hulett, S. Bayat, B. M. Abbott, A. R. Gendall, M. A. Perugini

This study identifies plant DHDPS inhibitors as a novel herbicide target, showing they inhibit lysine biosynthesis and demonstrate herbicidal activity against Arabidopsis thaliana.

bioRxiv · May 6, 2021Biochemistry

Crystal structure and site-directed mutagenesis of circular bacteriocin plantacyclin B21AG reveals cationic and aromatic residues important for antimicrobial activity

M. C. Gor, B. Vezina, R. M. McMahon, G. J. King, S. Panjikar, B. H. A. Rehm, J. L. Martin, A. T. Smith

The paper determines the crystal structure of plantacyclin B21AG and identifies key cationic and aromatic residues critical for its antimicrobial activity through site-directed mutagenesis.

bioRxiv · Jul 2, 2020Biochemistry