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Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
11 papers
Recent·Most cited
T. H. Hung, E. T. Y. Wu, P. Zeltins, A. Jansons, A. Ullah, N. Erbilgin, J. Bohlmann, J. Bousquet, I. Birol, S. Clegg, J. MacKay
BMC Genomics · Jan 27, 2024Peer-reviewedEvolutionary Biology
Y. Imoto, J. Xue, L. Luo, S. Raychaudhuri, K. Itoh, Y. Ma, G. E. Craft, A. H. Kwan, J. Mackay, T. Ha, S. Watanabe, P. J. Robinson
This study identifies a phospho-regulated interaction between Dyn1xA and Endophilin A1 via a unique C-terminal extension, essential for ultrafast endocytosis.
bioRxiv · Sep 21, 2023Cell Biology
J. K. Low, K. Patel, P. Solomon, A. Norman, P. Pachl, N. Jones, R. J. Payne, T. Passioura, H. Suga, L. J. Walport, J. Mackay
The paper uses mRNA display to identify high-affinity bromodomain-binding motifs not present in the human proteome, revealing novel binding modes and suggesting evolutionary pressure against strong binders.
bioRxiv · May 17, 2023Biochemistry
Y. Zhong, H. Moghaddas Sani, B. Paudel, J. Low, A. Silva, S. Mueller, C. Deshpande, S. Panjikar, X. Reid, M. Bedward, A. van Oijen, J. Mackay
The paper investigates how auxiliary domains in CHD4 modulate its activity, revealing common regulatory mechanisms across chromatin remodelling enzyme families.
bioRxiv · Jun 13, 2022 · PreprintBiochemistry
L. Loo, M. A. Waller, C. L. Moreno, A. J. Cole, A. O. Stella, O.-T. Pop, A.-K. Jochum, O. H. Ali, C. E. Denes, Z. Hamoudi, F. Chung, A. Aggarwal, J. K. K. Low, K. Patel, R. Siddique, , G. G. Neely
This study identifies LRRC15 as a host factor that suppresses SARS-CoV-2 infection and regulates antiviral and antifibrotic transcriptional programs in fibroblasts.
bioRxiv · Nov 9, 2021 · PreprintCell Biology
A. Norman, C. Franck, M. Christie, P. Hawkins, K. Patel, A. Ashhurst, A. Aggarwal, J. K. Low, R. Siddiquee, C. Ashley, M. Steain, J. A. Triccas, S. G. Turville, J. Mackay, T. Passioura, R. J. Payne
The paper identifies cyclic peptide ligands to the SARS-CoV-2 spike protein RBD using mRNA display, finding six high-affinity molecules with nanomolar dissociation constants.
ACS Central Science · Jun 23, 2021Peer-reviewedBiochemistry
J. Mackay, R. E. Hewett, N. T. Smith, T. L. Waters, J. S. Scandrett
The Foster method uses eDNA sampling and dual-target qPCR to rapidly detect clinically significant American Foulbrood disease in hives without dismantling them, enabling early intervention.
bioRxiv · Jun 18, 2021Microbiology
C. Counoupas, M. D. Johnson, A. Stella, D. H. Nguyen, A. Ferguson, A. Aggarwal, N. Bhattacharyya, A. Grey, K. Patel, R. Siddiquee, E. L. Stewart, O. Hutchings, C. Feng, N. G. G. Hansbro, U. Palendira, , J. A. Triccas
A BCG-adjuvanted vaccine provides sterilizing immunity against SARS-CoV-2 in mice, with high neutralizing antibody titers and Th1 responses.
bioRxiv · Dec 10, 2020 · PreprintMicrobiology
D. Doak, G. Denyer, J. Gerrard, J. Mackay, J. Allison
Peppy is a virtual reality tool designed to teach protein structure principles by allowing interactive exploration of secondary structure factors in a dynamic, 3D environment.
bioRxiv · Aug 8, 2019Biochemistry
Y. Zhong, B. P. Paudel, D. Ryan, J. Low, C. Franck, K. Patel, M. Benward, R. Payne, A. van Oijen, J. Mackay
This study investigates the mechanism of CHD4-mediated nucleosome sliding using single-molecule assays, revealing a decoupling of DNA translocation at entry and exit sides.
bioRxiv · Jun 27, 2019Biochemistry
J.-P. Verta, C.R. Landry, J. MacKay
The paper analyzes the genetic basis of transcriptional variation in a haploid/diploid plant system, identifying cis and trans effects and their phenotypic additivity.
bioRxiv · Jul 15, 2014 · PreprintGenomics