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S. Posada-Cespedes

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Evolutionary Biology· 1

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Assay:DNA methylation· 1 Organism:human· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1 Assay:whole-genome sequencing· 1

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G. Van Zyl· 1 shared H. F. Günthard· 1 shared H. Montazeri· 1 shared J. Kuipers· 1 shared N. Beerenwinkel· 1 shared R. Kouyos· 1 shared S.-Y. Rhee· 1 shared

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1 shared paperEvolutionary Biology

G. Van Zyl

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Evolutionary BiologybioRxivSep 25, 2020

Comparing mutational pathways to lopinavir resistance in HIV-1 subtypes B versus C

S. Posada-Cespedes, G. Van Zyl, H. Montazeri…·N. Beerenwinkel

This paper compares mutational pathways to lopinavir resistance in HIV-1 subtypes B and C using a probabilistic model, finding distinct initial mutations and diverse evolutionary pathways.

DOI 10.1371/journal.pcbi.1008363

humanDNA methylation

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