Author

S. Quack

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Biology Disciplines

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Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:virus· 1

Frequent Co-Authors

B. Canard· 1 shared C. E. Cameron· 1 shared D. Dulin· 1 shared F. S. Papini· 1 shared J. J. Arnold· 1 shared M. Depken· 1 shared M. Seifert· 1 shared P. van Nies· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiophysics

B. Canard

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1 paper

Recent·Most cited

The nucleotide addition cycle of the SARS-CoV-2 polymerase

S. C. Bera, M. Seifert, R. Kirchdoerfer, P. van Nies, Y. Wubulikasimu, S. Quack, F. S. Papini, J. J. Arnold, B. Canard, C. E. Cameron, M. Depken, D. Dulin

This study describes the mechanochemical behavior of the SARS-CoV-2 polymerase using magnetic tweezers, revealing three catalytic conformations and a thermal ratchet mechanism for nucleotide incorporation.

bioRxiv · Mar 27, 2021Biophysics