BiochemistrybioRxivPreprint
Protein thiol alterations drive aberrant phase separation in aging
T. Vignane, M. Hugo, C. Hoffmann…·M. Filipovic
This study shows that aging-related changes in cysteine posttranslational modifications alter protein phase separation, leading to aggregation and neurodegeneration.
DOI 10.1101/2023.11.07.566021