A transcriptome-wide meta-analysis reveals lack of cancer-cell intrinsic determinants of response to immune checkpoint blockade
Y. A. Guo, T. Kulshrestha, M. M. Chang…·A. Jacobsen Skanderup
This study performs a transcriptome-wide meta-analysis to identify determinants of immune checkpoint blockade response, finding that stromal factors, not cancer-cell intrinsic features, are key predictors across tumor types.