Author

F. Luciani

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 5 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 5 Approach:experimental assay· 5 Assay:scRNA-seq· 5 Organism:human· 4 Research Focus:differential expression· 3 Approach:statistical model· 3 Research Focus:clustering· 2 Organism:mouse· 2

Frequent Co-Authors

J. Samir· 2 shared K. Kedzierska· 2 shared M. Gupta· 2 shared S. Rizzetto· 2 shared A. A. Berry· 1 shared A. Carr· 1 shared A. D. Kelleher· 1 shared A. Eltahla· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersImmunology

J. Samir

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Self-reactive B cells traverse a perfect storm of somatic mutagenesis to cause a virus-induced autoimmune disease

C. Young, M. Singh, K. J. Jackson, M. A. Field, T. J. Peters, S. Angioletti-Uberti, D. Frenkel, S. Ravishankar, M. Gupta, J. J. Wang, D. Agapiou, M. L. Faulks, G. Al-Eryani, F. Luciani, T. P. Gordon, , C. C. Goodnow

The paper traces the evolution of autoantibodies in HCV-CV patients, revealing convergent somatic mutations and compromised solubility in pathogenic B cells.

bioRxiv · Jan 7, 2024Immunology

Global and cell type-specific immunological hallmarks of severe dengue progression

L. Ghita, Z. Yao, Y. Xie, V. Duran, B. H. Cagirici, J. Samir, I. Osman, O. L. Agudelo, A. M. Sanz, M. K. Sahoo, M. Robinson, R. M. Gelvez, N. Bueno, F. Luciani, B. A. Pinsky, , S. Einav

This study identifies DENV target cells and immunological changes in severe dengue progression using single-cell RNA-Seq and functional assays in children.

bioRxiv · Dec 11, 2022 · PreprintImmunology

The E-cadherin-ESR1-GRPR axis defines a sex-specific metastatic pathway in melanoma

J. H. Raymond, M. Schonau, V. Petit, Z. Aktary, F. Luciani, M. Wehbe, I. Davidson, C.-L. Tomasetto, F. Mahuteau-Betzer, B. Vergier, L. Larue, V. Delmas

This study identifies an E-cadherin-ER-GRPR axis that drives sex-specific melanoma metastasis and shows GRPR inhibition reduces metastasis in vivo.

bioRxiv · Dec 2, 2022 · PreprintCancer Biology

Single cell multi-omics reveals early elevated function and multiple fates within human progenitor exhausted CD8+ T cells

F. Luciani, J. Samir, P. Leung, K. Kedzierska, T. Nguyen, A. Lloyd, C. Cai, R. Bull, E. Keoshkerian, A. Eltahla, T. Peters, S. Gaudieri, M. Gupta, T. Adikari, R. Louie, , J.-L. Palgen

The paper identifies progenitor cells of T-cell exhaustion in acute HCV infection and shows their functional and phenotypic characteristics.

bioRxiv · Sep 9, 2021 · PreprintImmunology

A distinct CD115- erythro-myeloid precursor present at the maternal-embryonic interface and in the bone marrow of adult mice

S. Tikoo, R. Jain, B. Martinez, R. Song, M. Wielscher, S. Rizzetto, L. E. Shaw, A. J. Mitchell, M. E. Torres-Pacheco, F. Luciani, M. Farlik, J. Wong, S. Jung, S. T. Fraser, W. Weninger

The paper identifies a CD115- macrophage precursor in adult bone marrow that shares features with embryonic erythro-myeloid progenitors and is present at the maternal-embryonic interface.

bioRxiv · Jul 24, 2021 · PreprintImmunology

Atypical B cells are a normal component of immune responses to vaccination and infection in humans

H. J. Sutton, R. Aye, A. H. Idris, R. Vistein, E. Nduati, O. Kai, J. Mwacharo, L. Xi, X. Gao, D. Andrews, M. Koutsakos, T. H. O. Nguyen, M. Nekrasov, P. Milburn, A. Ethala, , I. A. Cockburn

This study identifies atypical B cells as a normal part of immune responses to vaccination and infection in humans, showing they are present in both malaria-exposed and healthy individuals.

bioRxiv · May 28, 2020 · PreprintImmunology