Author

A. Lloyd

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 2 Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:Arabidopsis· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

A. B. Shiels· 1 shared A. Eltahla· 1 shared A. J. Piaggio· 1 shared A. Rousselet· 1 shared A. W. Purcell· 1 shared A.-M. Chevre· 1 shared B. Hollingsworth· 1 shared C. Cai· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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1 shared paperEvolutionary Biology

A. B. Shiels

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Author profile →

4 papers

Recent·Most cited

Conserved allomorphs of MR1 drive specificity of MR1-restricted TCRs

T. V. Cornforth, N. A. Moyo, S. Cole, E. Lam, T. Lobry, R. Wolchinsky, A. Lloyd, K. Ward, E. M. Denham, G. S. Besra, N. Veerapen, P. T. Illing, J. P. Vivian, J. M. Raynes, J. Le Nours, , J. Dukes

The paper shows that MR1-restricted TCRs recognize an allelic variant of MR1 (MR1*04) present in healthy individuals, indicating that these TCRs are not cancer-specific and may react to both cancer and healthy cells.

bioRxiv · Jul 17, 2023Cancer Biology

Single cell multi-omics reveals early elevated function and multiple fates within human progenitor exhausted CD8+ T cells

F. Luciani, J. Samir, P. Leung, K. Kedzierska, T. Nguyen, A. Lloyd, C. Cai, R. Bull, E. Keoshkerian, A. Eltahla, T. Peters, S. Gaudieri, M. Gupta, T. Adikari, R. Louie, , J.-L. Palgen

The paper identifies progenitor cells of T-cell exhaustion in acute HCV infection and shows their functional and phenotypic characteristics.

bioRxiv · Sep 9, 2021 · PreprintImmunology

Locally Fixed Alleles: A method to localize gene drive to island populations

J. Sudweeks, B. Hollingsworth, D. V. Blondel, K. J. Campbell, S. Dhole, J. D. Eisemann, O. Edwards, J. Godwin, G. R. Howald, K. Oh, A. J. Piaggio, T. A. A. Prowse, J. V. Ross, J. R. Saah, A. B. Shiels, , A. Lloyd

This paper proposes a gene drive method to localize population elimination to island populations by targeting locally fixed alleles, showing limited spread to non-target populations.

bioRxiv · Sep 7, 2019Evolutionary Biology

Assessing the response of small RNA populations to allopolyploidy using resynthesized Brassica napus allotetraploids

P. Martinez Palacios, M.-P. Jacquemot, M. Tapie, A. Rousselet, M. Diop, C. Remoue, M. Falque, A. Lloyd, E. Jenczewski, G. Lassalle, A.-M. Chevre, C. Lelandais, M. Crespi, P. Brabant, J. Joets, K. Alix

This study examines how small RNA populations respond to allopolyploidy in Brassica napus allotetraploids, finding a shift from post-transcriptional to transcriptional gene silencing.

bioRxiv · Oct 19, 2018Evolutionary Biology