Author

S. S. Elsayed

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 5

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:bacteria (other)· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

C. Du· 3 shared G. van Wezel· 3 shared G. P. van Wezel· 2 shared J. Willemse· 2 shared M. H. Medema· 2 shared A. C. Chatziioannou· 1 shared A. E. Budding· 1 shared A. M. Kloosterman· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersMicrobiology

C. Du

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Author profile →

5 papers

Recent·Most cited

Probiotics supplementation to adult human small intestinal stoma microbiota causes dynamic increase in the community resistance to perturbations and nutrient utilization

J. Jansma, N. U. Thome, M. Schwalbe, A. C. Chatziioannou, S. S. Elsayed, G. van Wezel, P. van den Abbeele, S. van Hemert, S. El Aidy

This study shows how probiotic supplementation to adult human small intestinal stoma microbiota alters nutrient utilization and resistance to perturbations through changes in metabolite production.

bioRxiv · Jan 29, 2023 · PreprintMicrobiology

The plant stress hormone jasmonic acid evokes defensive responses in streptomycetes

A. van der Meij, S. S. Elsayed, C. Du, J. Willemse, T. M. Wood, N. I. Martin, J. M. Raaijmakers, G. van Wezel

This paper shows that plant hormones jasmonic acid and methyljasmonate alter growth, development, and antibiotic production in Streptomyces, with amino acid conjugation inactivating the hormone as a bacterial defense mechanism.

bioRxiv · Dec 23, 2022Microbiology

Taxonomic and metabolic diversity of Actinobacteria isolated from faeces of a 28,000-year-old mammoth

D. A. van Bergeijk, H. Augustijn, S. S. Elsayed, J. Willemse, V. J. Carrion, M. Urem, L. V. Grigoreva, M. Cheprasov, S. Grigariev, B. Wintermans, A. E. Budding, H. P. Spaink, M. H. Medema, G. van Wezel

The paper isolates and characterizes Actinobacteria from a 28,000-year-old mammoth's feces, revealing phylogenetic and metabolic differences from modern strains.

bioRxiv · Dec 22, 2022 · PreprintMicrobiology

New from old: discovery of the novel antibiotic actinomycin L in Streptomyces sp. MBT27

N. Machushynets, S. S. Elsayed, C. Du, M. A. Siegler, M. de la Cruz, O. Genilloud, T. Hankemeier, G. P. van Wezel

This paper discovers novel actinomycin derivatives, L1 and L2, produced by Streptomyces sp. MBT27 through metabolic analysis and molecular networking, showing their unique biosynthesis involving two metabolic pathways.

bioRxiv · Oct 12, 2021 · PreprintMicrobiology

Integration of machine learning and pan-genomics expands the biosynthetic landscape of RiPP natural products

A. M. Kloosterman, P. Cimermancic, S. S. Elsayed, C. Du, M. Hadjithomas, M. S. Donia, M. A. Fischbach, G. P. van Wezel, M. H. Medema

The paper introduces decRiPPter, a machine learning and pan-genomic approach to discover novel RiPP classes, identifying 42 new candidate families from Streptomyces genomes.

bioRxiv · May 19, 2020Microbiology