Author

M. Schwalbe

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Research Focus:differential expression· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:metagenomics· 2

Frequent Co-Authors

S. El Aidy· 3 shared A. Danewalia· 2 shared B. Dalile· 2 shared E. V. Prochownik· 2 shared H. Wang· 2 shared J. A. Mandel· 2 shared J. Lu· 2 shared J. Wang· 2 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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3 shared papersMicrobiology

S. El Aidy

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Probiotics supplementation to adult human small intestinal stoma microbiota causes dynamic increase in the community resistance to perturbations and nutrient utilization

J. Jansma, N. U. Thome, M. Schwalbe, A. C. Chatziioannou, S. S. Elsayed, G. van Wezel, P. van den Abbeele, S. van Hemert, S. El Aidy

This study shows how probiotic supplementation to adult human small intestinal stoma microbiota alters nutrient utilization and resistance to perturbations through changes in metabolite production.

bioRxiv · Jan 29, 2023 · PreprintMicrobiology

Gut microbiota transplantation drives the adoptive transfer of colonic genotype-phenotype characteristics between mice lacking catestatin and their wild type counterparts

P. Gonzalez-Davila, M. Schwalbe, A. Danewalia, R. Wardenaar, B. Dalile, K. Verbeke, S. K. Mahata, S. El Aidy

This study shows that gut microbiota transplantation from CST-KO mice to wild-type mice induces colonic fibrosis and tight junction impairment, suggesting a causal role for microbiota in intestinal dyshomeostasis linked to catestatin deficiency.

bioRxiv · Feb 24, 2022Microbiology

Catestatin selects for the colonization of antimicrobial-resistant gut bacterial communities

P. Gonzalez-Davila, M. Schwalbe, A. Danewalia, B. Dalile, K. Verbeke, S. K. Mahata, S. El Aidy

This study shows that catestatin (CST) alters gut microbiota composition and promotes antimicrobial resistance in CST-KO mice, with implications for inflammatory bowel disease.

bioRxiv · Oct 11, 2021Microbiology

Patient-Derived Mutant Forms of NFE2L2/NRF2 Drive Aggressive Murine Hepatoblastomas

H. Wang, J. Lu, J. A. Mandel, W. Zhang, M. Schwalbe, J. Gorka, Y. Liu, B. Marburger, J. Wang, S. Ranganathan, E. V. Prochownik

This study shows that patient-derived NFE2L2 mutants drive aggressive hepatoblastomas in mice by accelerating tumor growth and promoting necrosis and cyst formation.

bioRxiv · Sep 13, 2020Cancer Biology

Acquired deficiency of the peroxisomal enzyme enoyl-CoA hydratase/3-hydroxyacyl CoA dehydrogenase is a metabolic vulnerability in hepatoblastoma

H. Wang, X. Chen, M. Schwalbe, J. E. Gorka, J. A. Mandel, J. Wang, J. Lu, E. S. Goetzman, S. Dobrowolski, E. V. Prochownik

This study shows that reducing the peroxisomal enzyme Ehadh in hepatoblastoma makes tumors more susceptible to a fatty acid metabolite, suggesting a potential metabolic therapy.

bioRxiv · Aug 24, 2020 · PreprintCancer Biology