Author

T. Hankemeier

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Microbiology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:bacteria (other)· 3 Assay:metabolomics· 3 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:benchmarking· 1 Assay:proteomics· 1

Frequent Co-Authors

G. P. van Wezel· 2 shared N. Machushynets· 2 shared A. C. Harms· 1 shared A. Harms· 1 shared A. J. van Zonneveld· 1 shared A. Junaid· 1 shared A. K. Aatsinki· 1 shared A. M. Dickens· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 9 mutual co-author links

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2 shared papersMicrobiology

G. P. van Wezel

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Tracer-based metabolomics for profiling nitric oxide metabolites in a 3D microvessel-on-a-chip model

K. Pandian, L. Huang, A. Junaid, A. C. Harms, A. J. van Zonneveld, T. Hankemeier

This paper develops a tracer-based metabolomics approach to measure NO metabolites in 2D and 3D endothelial models, showing that 3D models with unidirectional flow better mimic physiological conditions than 2D static cultures.

bioRxiv · Dec 3, 2023Cell Biology

Comparative metabolomics and microbiome analysis of Ethanol vs. OMNImet/gene GUT fecal stabilization

H. Isokaanta, L. Pinto da Silva, N. Karu, T. Kallonen, A. K. Aatsinki, T. Hankemeier, L. Schimmel, E. Diaz, T. Hyotylainen, P. C. Dorrestein, R. Knight, M. Oresic, R. K. Daouk, A. M. Dickens, S. Lamichhane

This study compares the stability of fecal metabolome and microbiome using 95% ethanol and commercial kits under different storage conditions, finding comparable results to flash freezing.

bioRxiv · Aug 29, 2023 · PreprintBiochemistry

New from old: discovery of the novel antibiotic actinomycin L in Streptomyces sp. MBT27

N. Machushynets, S. S. Elsayed, C. Du, M. A. Siegler, M. de la Cruz, O. Genilloud, T. Hankemeier, G. P. van Wezel

This paper discovers novel actinomycin derivatives, L1 and L2, produced by Streptomyces sp. MBT27 through metabolic analysis and molecular networking, showing their unique biosynthesis involving two metabolic pathways.

bioRxiv · Oct 12, 2021 · PreprintMicrobiology

Discovery of Novel Glycerolated Quinazolinones from Streptomyces sp. MBT27

G. P. van Wezel, N. Machushynets, C. Wu, S. Elsayed, T. Hankemeier

This study identifies novel glycerolated quinazolinones produced by Streptomyces sp. MBT27 under glycerol-induced conditions and elucidates their biosynthetic pathway.

bioRxiv · Dec 27, 2018Microbiology

High-resolution analysis of the peptidoglycan composition in Streptomyces coelicolor

G. van Wezel, L. van der Aart, G. K. Spijksma, A. Harms, W. Vollmer, T. Hankemeier

This study analyzes peptidoglycan composition in Streptomyces coelicolor during growth and sporulation, revealing dynamic changes in cross-linking and hydrolysis.

bioRxiv · May 10, 2018Biochemistry