Cell BiologybioRxiv
Genome-edited zebrafish model of ABCC8 loss-of-function disease
J. M. Ikle, R. C. Tryon, S. S. Singareddy…·C. G. Nichols
This paper creates a zebrafish model of ABCC8 loss-of-function disease by introducing a SUR1 truncation mutation and shows it mimics key features of congenital hyperinsulinism seen in mice.
DOI 10.1080/19382014.2022.2149206