Author

S. Scaramuzza

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Gambus· 2 shared T. Natsume· 2 shared D. Poovathumkadavil· 1 shared F. Romero· 1 shared J. Herrero Ruiz· 1 shared M. Henklewska· 1 shared M. Kanemaki· 1 shared M. Muste Sadurni· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersCell Biology

A. Gambus

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2 papers

Recent·Most cited

Characterising replisome disassembly in human cells

R. Jones, J. Herrero Ruiz, S. Scaramuzza, S. Nath, M. Henklewska, T. Natsume, F. Romero, M. Kanemaki, A. Gambus

This study characterizes replisome disassembly in human cells, showing that Cullin2, LRR1, and p97 are required, and that replication stress occurs with inhibitor treatment.

bioRxiv · Jul 12, 2022Cell Biology

Ubiquitin ligase TRAIP plays an essential role during the S-phase of unperturbed cell cycle in the resolution of DNA replication - transcription conflicts

S. Scaramuzza, M. Muste Sadurni, D. Poovathumkadavil, T. Natsume, P. Rojas, M. T. Kanemaki, M. Saponaro, A. Gambus

This study identifies TRAIP's role in preventing DNA damage during S-phase by resolving replication-transcription conflicts, leading to cell cycle arrest and senescence upon TRAIP depletion.

bioRxiv · Mar 23, 2022 · PreprintCell Biology