PhysiologybioRxiv
Piezo1-induced durotaxis of pancreatic stellate cells depends on TRPC1 and TRPV4 channels
I. Budde, A. Schlichting, D. Ing…·Z. Petho
This study identifies Piezo1, TRPC1, and TRPV4 as mechanosensitive ion channels crucial for durotaxis in pancreatic stellate cells, which contributes to pancreatic cancer progression.
DOI 10.1242/jcs.263846