Author

S. Siebert

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Evolutionary Biology· 2 Biochemistry· 1 Cancer Biology· 1 Cell Biology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 3 Approach:experimental assay· 3 Research Focus:gene regulatory network inference· 3 Organism:human· 3 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Research Focus:cell signaling & trafficking· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

C. Juliano· 2 shared C. Munro· 2 shared C. W. Dunn· 2 shared F. Zapata· 2 shared M. Howison· 2 shared A. A. Kazrani· 1 shared A. Blais· 1 shared A. Damian-Serrano· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersPlant Biology

C. Juliano

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

BCL7 proteins, metazoan-specific subunits of the mammalian SWI/SNF complex, bind the nucleosome core particle

D. Diaz, A. A. Kazrani, F. Martin, J. Lafouge, S. Siebert, C. Birck, A. Blais, E. Bergamin

This study identifies BCL7 proteins as nucleosome-binding subunits of the mSWI/SNF complex and shows cancer mutations reduce their affinity for nucleosomes.

bioRxiv · Mar 17, 2023 · PreprintBiochemistry

Evolution of gene expression across species and specialized zooids in Siphonophora

C. Munro, F. Zapata, M. Howison, S. Siebert, C. W. Dunn

The paper uses RNA-seq to analyze gene expression in zooids and tissues across seven siphonophore species, identifying species- and zooid-specific genes and introducing a phylogenetic method to study expression evolution.

bioRxiv · Jul 30, 2021Evolutionary Biology

Self-organized yolk sac-like organoids allow for scalable generation of multipotent hematopoietic progenitor cells from human induced pluripotent stem cells

N. Tamaoki, S. Siebert, T. Maeda, N.-H. Ha, M. L. Good, Y. Huang, S. K. Vodnala, J. J. H. Mora, U. Naoya, J. F. Tisdale, C. L. Sweeney, U. Choi, J. Brault, S. Koontz, H. L. Malech, , R. Vizcardo

This study develops yolk sac-like organoids from hiPSCs to generate multipotent hematopoietic progenitor cells in a scalable and xeno-free system.

bioRxiv · Apr 25, 2021Cell Biology

Molecular Mechanisms Driving Bistable Switch Behavior in Xylem Cell Differentiation

G. M. Turco, J. Rodriguez-Medina, S. Siebert, D. Han, H. Vahldick, C. N. Shulse, B. J. Cole, C. Juliano, D. E. Dickel, M. A. Savageau, S. M. Brady

The paper models the molecular mechanisms of bistable switching in xylem cell differentiation using whole root and single-cell data, identifying VND7's role and a novel regulatory cycle.

bioRxiv · Feb 8, 2019Plant Biology

Systems-level properties of EGFR/Ras/ERK signalling amplify local signals to generate gene expressionplasticity

A. E. Davies, T. E. Gillies, S. Siebert, M. Pargett, S. J. Tobin, A. R. Ram, C. Juliano, G. Quon, M. J. Bissell, J. G. Albeck

The paper shows that EGFR/Ras/ERK signaling in invasive breast cancer cells produces more dynamic and disordered ERK activity, leading to heterogeneous gene expression compared to non-malignant cells.

bioRxiv · Nov 9, 2018 · PreprintCancer Biology

Improved phylogenetic resolution within Siphonophora (Cnidaria) with implications for trait evolution

C. Munro, S. Siebert, F. Zapata, M. Howison, A. Damian-Serrano, S. H. Church, F. E. Goetz, P. R. Pugh, S. H. D. Haddock, C. W. Dunn

This study improves the phylogenetic resolution of Siphonophora using new transcriptome data and existing datasets, revealing new clades and supporting the hypothesis that monoecy evolved twice.

bioRxiv · Jan 20, 2018Evolutionary Biology