T. Maeda

A fatal case of peritonitis caused by Dysgonomonas capnocytophagoides harboring the novel metallo-beta-lactamase gene blaDYB-1

The paper reports a fatal peritonitis case caused by Dysgonomonas capnocytophagoides carrying a novel metallo-beta-lactamase gene and an ermFS gene associated with multidrug resistance.

Multi-dimensional antibiotic resistance time series reveals the phenotype-based fitness landscape for Escherichia coli

The paper infers a phenotype-based fitness landscape for antibiotic resistance in Escherichia coli using multi-dimensional time-series drug resistance data to predict evolutionary trajectories.

Transcriptional regulation of sphingolipid metabolism in budding yeast

This study identifies Com2 as a master transcriptional regulator of sphingolipid metabolism in yeast, showing it upregulates Ypk1 expression to control sphingolipid biosynthesis and response to environmental stress.

Self-organized yolk sac-like organoids allow for scalable generation of multipotent hematopoietic progenitor cells from human induced pluripotent stem cells

This study develops yolk sac-like organoids from hiPSCs to generate multipotent hematopoietic progenitor cells in a scalable and xeno-free system.

Behavioural synchronization in a multilevel society of feral horses

The paper models behavioural synchronization in feral horses, finding that synchronization occurs both within and across social units, with stronger internal synchronization.

Asymbiotic mass production of the arbuscular mycorrhizal fungus Rhizophagus clarus

This study shows that combining strigolactone and methyl jasmonate with myristate and organic nitrogen in asymbiotic cultures of Rhizophagus clarus HR1 increases spore production and infectivity, supporting plant growth.

Reduction of Short-Chain Fatty Acid-Producing Gut Microbiota Leads to Transition from Rapid-Eye-Movement Sleep Behavior Disorder to Parkinson's Disease

The paper analyzes gut microbiota in RBD and PD patients, finding increased Akkermansia and decreased SCFA-producing bacteria in PD, suggesting a link between gut dysbiosis and disease progression.

Iron limitation by transferrin promotes simultaneous cheating of pyoverdine and exoprotease in Pseudomonas aeruginosa

The paper shows that using transferrin as an iron chelator selects for mutants lacking both pyoverdine and exoprotease production in Pseudomonas aeruginosa.

Chloroplast acquisition without the gene transfer in kleptoplastic sea slugs, Plakobranchus ocellatus

This study sequenced the genome of a kleptoplastic sea slug and found no evidence of algal gene transfer to the nucleus, showing photosynthesis can occur without nuclear gene transfer.

High-throughput laboratory evolution and evolutionary constraints in Escherichia coli

This study uses high-throughput lab evolution of E. coli to identify evolutionary constraints and trade-offs in antibiotic resistance.

A Germinal Center-Associated Microenvironmental Signature Reflects Malignant Phenotype and Outcome of Diffuse Large B-cell Lymphoma

The paper identifies a germinal center-associated microenvironmental signature in DLBCL that correlates with prognosis and molecular features, showing its impact on clinical outcomes.

Circulating Th17.1 cells as candidate for prediction of therapeutic response to abatacept in patients with rheumatoid arthritis: exploratory research

This study identifies Th17.1 cells as a biomarker predicting response to abatacept in rheumatoid arthritis patients.

Structure-specific regulation of nutrient absorption, metabolism and transfer in arbuscular mycorrhizal fungi

The paper analyzes structure-specific gene expression in arbuscular mycorrhizal fungi to understand nutrient absorption, metabolism, and transfer across different developmental stages.

PP2AB55δ Responsible for the High Initial Rates of Alcoholic Fermentation in Sake Yeast Strains of Saccharomyces cerevisiae

This study identifies PP2AB55δ as a mediator of high fermentation rates in sake yeast strains through the TORC1-Greatwall-PP2AB55δ pathway.