Author

U. Choi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell type annotation· 4 Organism:E. coli· 3 Research Focus:development & morphogenesis· 2 Assay:proteomics· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

C.-R. Lee· 3 shared S. H. Park· 3 shared H. B. Lee· 2 shared A. AlJanahi· 1 shared A. Gin· 1 shared B.-C. Lee· 1 shared C. Dunbar· 1 shared C. L. Sweeney· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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3 shared papersMicrobiology

C.-R. Lee

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Lytic transglycosylase repertoire diversity enables daughter cell separation and antibiotic resistance in Escherichia coli under acidic stress

C.-R. Lee, J. E. Son, S. H. Park, U. Choi

This study identifies MltE and MltC as critical lytic transglycosylases that enable Escherichia coli survival and antibiotic resistance under acidic stress by facilitating daughter cell separation and maintaining membrane integrity.

bioRxiv · Feb 16, 2024 · PreprintMicrobiology

Impact of CRISPR/HDR-editing versus lentiviral transduction on long-term engraftment and clonal dynamics of HSPCs in rhesus macaques

B.-C. Lee, A. Gin, C. Wu, K. Singh, M. Grice, R. Mortlock, D. Abraham, X. Fan, Y. Zhou, A. AlJanahi, U. Choi, S. S. de Ravin, T. Shin, S. Hong, C. Dunbar

This study compares CRISPR/HDR and lentiviral transduction effects on HSPC engraftment and clonal dynamics in rhesus macaques, finding HDR-edited cells decline rapidly while lentiviral cells persist longer.

bioRxiv · Dec 13, 2023Cell Biology

Coordinated and distinct LD-transpeptidase-independent roles of peptidoglycan carboxypeptidases DacC and DacA in stress adaptation and cell shape maintenance

U. Choi, S. H. Park, H. B. Lee, C.-R. Lee

This study identifies distinct and coordinated roles of DacC and DacA in stress adaptation and cell shape maintenance in E. coli, independent of LD-transpeptidases and involving interactions with PBPs.

bioRxiv · Sep 6, 2022 · PreprintMicrobiology

Divergent LD-transpeptidase-independent effects of peptidoglycan carboxypeptidases on intrinsic ss-lactam and vancomycin resistance

S. H. Park, U. Choi, S.-H. Ryu, H. B. Lee, J.-W. Lee, C.-R. Lee

This study shows that peptidoglycan carboxypeptidases in E. coli and B. subtilis affect vancomycin and β-lactam resistance independently of LD-transpeptidases, with deletion causing β-lactam sensitivity and vancomycin resistance.

bioRxiv · Apr 4, 2022 · PreprintMicrobiology

Self-organized yolk sac-like organoids allow for scalable generation of multipotent hematopoietic progenitor cells from human induced pluripotent stem cells

N. Tamaoki, S. Siebert, T. Maeda, N.-H. Ha, M. L. Good, Y. Huang, S. K. Vodnala, J. J. H. Mora, U. Naoya, J. F. Tisdale, C. L. Sweeney, U. Choi, J. Brault, S. Koontz, H. L. Malech, , R. Vizcardo

This study develops yolk sac-like organoids from hiPSCs to generate multipotent hematopoietic progenitor cells in a scalable and xeno-free system.

bioRxiv · Apr 25, 2021Cell Biology