Author

D. Diaz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Biochemistry· 1 Biophysics· 1 Immunology· 1 Pharmacology & Toxicology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Organism:human· 3 Research Focus:protein folding & dynamics· 3 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

A. Care· 2 shared I. Boyton· 2 shared L. Collins-Praino· 2 shared A. A. Kazrani· 1 shared A. Allali-Hassani· 1 shared A. Blais· 1 shared A. Chaudhuri· 1 shared A. Dong· 1 shared

Activity by Year

2018-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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2 shared papersBioengineering

A. Care

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

In vivo fate of systemically administered encapsulin protein nanocages and implications for their use in targeted drug delivery

C. Rennie, C. Sives, I. Boyton, D. Diaz, C. A. Gorrie, O. Vittorio, L. Collins-Praino, A. Care

This study investigates the in vivo behavior of encapsulin nanocages in mice, showing their safety, immunogenicity, and clearance via the mononuclear phagocyte system.

bioRxiv · Jul 16, 2023 · PreprintBioengineering

β-hydroxybutyrate is a metabolic regulator of proteostasis in the aged and Alzheimer disease brain

S. S. Madhavan, S. Roa Diaz, S. Peralta, M. Nomura, C. D. King, A. Lin, D. Bhaumik, S. Shah, T. Blade, W. Gray, M. Chamoli, B. Eap, O. Panda, D. Diaz, T. Y. Garcia, , J. C. Newman

This study identifies β-hydroxybutyrate as a metabolic regulator of protein solubility in aging and Alzheimer's disease, showing it reduces insolubility of pathological proteins like amyloid-β.

bioRxiv · Jul 3, 2023Physiology

BCL7 proteins, metazoan-specific subunits of the mammalian SWI/SNF complex, bind the nucleosome core particle

D. Diaz, A. A. Kazrani, F. Martin, J. Lafouge, S. Siebert, C. Birck, A. Blais, E. Bergamin

This study identifies BCL7 proteins as nucleosome-binding subunits of the mSWI/SNF complex and shows cancer mutations reduce their affinity for nucleosomes.

bioRxiv · Mar 17, 2023 · PreprintBiochemistry

Exploring the Self-Assembly of Encapsulin Protein Nanocages from Different Structural Classes

I. Boyton, S. C. Goodchild, D. Diaz, A. Elbourne, L. Collins-Praino, A. Care

This study examines the disassembly and reassembly of three encapsulin nanocages with different structural classes, revealing variations in their stability under various conditions.

bioRxiv · Jun 6, 2021 · PreprintBiophysics

Antibody recognition of the Pneumovirus fusion protein trimer interface

J. Huang, D. Diaz, J. J. Mousa

This study identifies a novel epitope on the hMPV F protein recognized by neutralizing antibodies, revealing structural dynamics and glycan interactions important for vaccine design.

bioRxiv · May 20, 2020Immunology

Identification and Characterization of the First Fragment Hits for SETDB1 Tudor Domain

P. Mader, R. Mendoza-Sanchez, A. Iqbal, A. Dong, E. Dobrovetsky, V. Corless, S. Liew, S. Houliston, R. Ferreira De Freitas, D. Smil, C. Dela Sena, S. Kennedy, D. Diaz, H. Wu, L. Dombrovski, , C. Arrowsmith

The paper identifies small molecule fragments that bind to the tudor domain of SETDB1 and describes their binding modes and biophysical properties.

Bioorganic & Medicinal Chemistry · Sep 1, 2019Peer-reviewedPharmacology & Toxicology

Glial cells in the heart? Replicating the diversity of the myocardium with low-cost 3D models

J. R. Soucy, J. Askaryan, D. Diaz, A. N. Koppes, N. Annabi, R. Koppes

The paper develops 3D cardiac tissue models to study the role of non-muscle cells in heart function, showing that Schwann cells affect cardiomyocyte electrical coupling.

bioRxiv · Apr 23, 2018Bioengineering