S. Small

Arterial effects of anthracycline: structural and inflammatory assessments in non-human primates and lymphoma patients using 18F-FDG positron emission tomography

This study evaluates anthracycline-induced arterial injury in non-human primates and lymphoma patients using histopathology and PET/CT, finding increased fibrosis in primates but no inflammation in patients.

Predictive modeling reveals that higher-order cooperativity drives transcriptional repression in a synthetic developmental enhancer

The paper uses thermodynamic models to show that higher-order cooperativity between transcription factors drives transcriptional repression in a synthetic enhancer.

Suboptimal intermediates underlie evolution of the Bicoid homeodomain

The paper shows that suboptimal intermediates in the evolution of the Bicoid homeodomain enabled further evolutionary changes through epistatic interactions.

Design and Optimization Protocol for High-Dimensional Immunophenotyping Assays using Spectral Flow Cytometry

The paper provides a protocol for designing and optimizing high-dimensional spectral flow cytometry panels, addressing challenges in panel complexity and data analysis.