Reduction of Short-Chain Fatty Acid-Producing Gut Microbiota Leads to Transition from Rapid-Eye-Movement Sleep Behavior Disorder to Parkinson's Disease
H. Nishiwaki, T. Hamaguchi, M. Ito, T. Ishida, T. Maeda, K. Kashihara, Y. Tsuboi, J. Ueyama, S. Teppei, H. Mori, K. Kurokawa, M. Katsuno, M. Hirayama, K. Ohno
The paper analyzes gut microbiota in RBD and PD patients, finding increased Akkermansia and decreased SCFA-producing bacteria in PD, suggesting a link between gut dysbiosis and disease progression.
bioRxiv · Aug 7, 2020 · PreprintMicrobiology