Cell BiologybioRxivPreprint
Hidden pathway for cytokine receptor activation: Structural insights into a marine sponge-derived lectin that activates the thrombopoietin receptor via recognition of the fucose moiety
H. Watari, H. Kageyama, N. Masubuchi…·R. Sakai
A marine sponge-derived lectin activates the thrombopoietin receptor by promoting dimerization and exhibits synergy with thrombopoietin, affecting receptor internalization.
DOI 10.1101/2021.10.29.466502