POMK Regulates Dystroglycan Function via LARGE-mediated Elongation of Matriglycan
A. S. Walimbe, H. Okuma, S. Joseph, T. Yang, T. Yonekawa, J. M. Hord, D. Venzke, M. E. Anderson, S. Torelli, A. Manzur, M. Devereaux, M. Cuellar, S. Prouty, S. Ocampo Landa, L. Yu, , K. P. Campbell
This study shows that POMK phosphorylates core M3 to enable LARGE to elongate matriglycan on dystroglycan, preventing muscular dystrophy.
bioRxiv · Apr 6, 2020Biochemistry