Author

S. V. Boddul

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:benchmarking· 1 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

F. Wermeling· 3 shared Y. Shen· 3 shared Z. Kasza· 3 shared L. Jiang· 2 shared V. S. Iyer· 2 shared A. Espinosa· 1 shared B. Raposo· 1 shared D. P. Lane· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersImmunology

F. Wermeling

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Dnmt3a mutations limit normal and autoreactive Tfh differentiation

Y. Shen, Z. Li, S. V. Boddul, Z. Kasza, A. Espinosa, L. Klareskog, F. Wermeling

This study shows that Dnmt3a mutations impair Tfh differentiation, contributing to autoimmune joint inflammation and reduced immune responses.

bioRxiv · Feb 16, 2024 · PreprintImmunology

CRISPR enriches for cells with mutations in a p53-related interactome, and this can be inhibited.

L. Jiang, K. Ingelshed, Y. Shen, S. V. Boddul, V. S. Iyer, Z. Kasza, S. Sedimbi, D. P. Lane, F. Wermeling

The paper shows that CRISPR enriches cells with p53-related mutations and demonstrates that transient p53 inhibition can suppress this effect.

bioRxiv · Mar 10, 2021 · PreprintCancer Biology

A rapid CRISPR competitive assay for in vitro and in vivo discovery of potential drug targets affecting the hematopoietic system

Y. Shen, L. Jiang, V. S. Iyer, B. Raposo, S. V. Boddul, Z. Kasza, F. Wermeling

This paper introduces a CRISPR-based assay to identify drug targets affecting hematopoietic cells by analyzing genotype enrichment in mixed CRISPR populations.

bioRxiv · Mar 8, 2021Immunology