PhysiologybioRxivPreprint
Neutrophil Peptidylarginine Deiminase 4 is Essential for Detrimental Age-related Cardiac Remodeling and Dysfunction in Mice
S. Van Bruggen, S. Kraisin, J. Van Wauwe…·K. Martinod
This study shows that neutrophil PAD4 deletion protects against age-related cardiac dysfunction and fibrosis in mice by affecting the CXCL1-CXCR2 axis.
DOI 10.1101/2022.03.14.484062