Cell BiologybioRxivPreprint
The ER membrane protein complex governs lysosomal turnover of a mitochondrial tail-anchored protein, BNIP3, to restrict mitophagy
J. M. Delgado, L. W. Shepard, S. W. Lamson…·C. J. Shoemaker
This study identifies the ER membrane protein complex as a key regulator of lysosomal BNIP3 turnover, independent of autophagy, and highlights its role in modulating mitophagy and TA protein quality control.
DOI 10.1101/2023.03.22.533681