Cell BiologybioRxiv
Respiration enhances TDP-43 toxicity, but TDP-43 retains some toxicity in the absence of respiration
S.-K. Park, S. Park, S. W. Liebman
This paper shows that TDP-43 is more toxic in yeast under respiratory conditions but remains toxic without respiration, suggesting reactive oxygen species may enhance its toxicity.
DOI 10.1016/j.jmb.2019.03.014