MicrobiologybioRxiv
Developing a newborn rat model of meningitis without concomitant bacteremia by intraventricular injection of K1 (-) Escherichia coli
W. S. Park, S. Y. AHN, Y. S. Chang…·S. Y. JOO
This study develops a newborn rat model of meningitis without systemic bacteremia using intraventricular injection of K1-negative E. coli, showing dose-dependent survival and brain injury.
DOI 10.1111/ped.14108