Author

Samantha Elizalde

University of Chicago Medical Center

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Cell Biology· 1

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Approach:statistical model· 1

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Kathryn Sanchez· 1 shared Miriam S. DomowicziD· 1 shared Nancy B. SchwartziD· 1 shared

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2026-2026 · peak 1/yr

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Kathryn Sanchez

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1 paper

Recent·Most cited

Cell BiologybioRxivPreprintOct 14, 2026

The role of the NLRP3 inflammasome in a CLN2 mouse model of neuroinflammation

Kathryn Sanchez, Samantha Elizalde, Nancy B. Schwartz, Miriam S. Domowicz

This study investigates the role of the NLRP3 inflammasome in a CLN2 mouse model, showing that inflammasome activation occurs at 3 months and that its inhibition reduces neuroinflammation.

DOI 10.64898/2026.10.12.758052

mousebulk RNA-seq

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