Sarah A. Teichmann

This study uses single-cell RNA sequencing to analyze stromal cell changes in murine melanoma, identifying distinct CAF populations and their roles in immune suppression across tumor development.

The paper proposes the Human Cell Atlas project to catalog all human cell types through molecular profiling and connects this data with classical cellular descriptions.

The paper uses single-cell RNA sequencing and computational modeling to resolve CD4+ T cell fate bifurcation during Plasmodium infection, showing external influence on fate decisions by monocytes.

This paper introduces TraCeR, a method to infer full-length TCR sequences from single-cell RNA-seq, revealing clonal relationships and linking them to T cell functional states in Salmonella infection.