Author

Sean J. Ihn

University of Toronto

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:metagenomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Alexander F. PalazzoiD· 2 shared Eliza S. Lee· 1 shared Harrison W. SmithiD· 1 shared Hyun O. LeeiD· 1 shared Jack F. GreenblattiD· 1 shared Laura Farlam-Williams· 1 shared Leticia Scalize de Olivera· 1 shared Nevraj S. Kejiou· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersMolecular Biology

Alexander F. PalazzoORCID

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2 papers

Recent·Most cited

Molecular BiologyLife Science AlliancePeer-reviewedDec 3, 2024

N-6-methyladenosine (m6A) Promotes the Nuclear Retention of mRNAs with Intact 5' Splice Site Motifs

Eliza S. Lee, Harrison W. Smith, Yifan E. Wang…·Alexander F. Palazzo

The paper shows that m6A modification facilitates nuclear retention of mRNAs with intact 5' splice site motifs through interactions with YTHDC1/YTHDC2, ZFC3H1, and U1-70K.

13 citations

humanyeast

𝕏 PostBluesky

Cell BiologybioRxivPreprintFeb 7, 2024

Cytoplasmic protein-free mRNA induces stress granules by two G3BP1/2-dependent mechanisms

Sean J. Ihn, Laura Farlam-Williams, Alexander F. Palazzo, Hyun O. Lee

The paper shows that protein-free mRNA induces stress granules via two G3BP1/2-dependent mechanisms, one involving PKR and eIF2 phosphorylation, and another independent of PKR and phospho-eIF2.

3 citations

humanmetagenomics

𝕏 PostBluesky