Author

Sean Keegan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Caroline P. Bullock· 2 shared Sol ShenkeriD· 2 shared Adam S. Lazorchak· 1 shared Alex SmashnoviD· 1 shared Amy Lundberg· 1 shared Anja F. Hohmann· 1 shared Anne E. DodsoniD· 1 shared Ashish YeriiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersImmunology

Caroline P. Bullock

Mutual co-authors in cluster

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintJan 23, 2026

Dual-inactivation of Regnase-1 and SOCS1 rewires exhausted CD8+ T cell fate to enhance anti-tumor functionality

Isabelle Le Mercier, David Monteiro, Katarina Halpin-Veszeleiova…·Micah J. Benson

This study identifies Regnase-1 and SOCS1 dual-inactivation as a strategy to enhance anti-tumor functionality of CD8+ T cells by rewiring their differentiation and effector state.

2 citations

mousegenetic perturbation / CRISPR

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Pharmacology & ToxicologyMolecular TherapyPeer-reviewedSep 5, 2025

A Precision Gene Engineered B Cell Medicine Producing Sustained Levels of Active Factor IX for Hemophilia B Therapy

Hanlan Liu, Swati Singh, Timothy Mullen…·Richard A. Morgan

This paper describes a gene-engineered B Cell Medicine (BE-101) that produces sustained active factor IX for hemophilia B therapy, showing durable and redosable effects in mice.

8 citationstop 3%

mouseexperimental assay

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