Genetic, Clinical Underpinnings of Brain Change Along Two Neuroanatomical Dimensions of Clinically-defined Alzheimer's Disease
J. Wen, Z. Yang, I. Nasrallah, Y. Cui, G. Erus, D. Srinivasan, A. Abdulkadir, E. Mamourian, I. Skampardoni, G. Hwang, A. Singh, M. Bergman, J. Bao, E. Varol, Z. Zhou, , Sh
This study identifies two brain atrophy dimensions in Alzheimer's disease using Surreal-GAN and links them to genetic and clinical factors, revealing distinct pathological mechanisms.
bioRxiv · Sep 16, 2022 · PreprintBioengineering