NeuroscienceMolecular NeurodegenerationPeer-reviewed
Amyloid plaque deposition accelerates tau propagation via activation of microglia in a humanized APP mouse model
Kevin A. Clayton, Jean-Christophe Delpech, Shawn Herron…·Tsuneya Ikezu
The paper shows that amyloid plaques accelerate tau propagation in mice by activating microglia, which secrete more extracellular vesicles.
245 citationstop 1%