Kai K. Ewert

This study shows that MVL5-based micellar nanoparticles enhance paclitaxel solubility and cytotoxicity in cancer cells, with PEGylation improving cellular uptake and penetration.

This paper demonstrates that acidic conditions enhance EV-liposome fusion without additional fusogens, supported by FRET and microscopy, and suggests implications for drug delivery.

This paper investigates the interactions between tau protein and anionic liposomes, revealing distinct complexes and phase-separated coacervates under varying ionic conditions.

This paper develops a library of PEG-lipids to enhance paclitaxel solubility and cytotoxicity in fluid micellar nanoparticles, finding that double-PEG-lipid 2k2 significantly improves solubility and efficacy.

This study shows that lipids with negative spontaneous curvature, like DOPE and GMO, reduce paclitaxel solubility in liposomes, making them unsuitable for drug delivery.