Author

Shivanshu Chandan

Central University of Haryana

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Immunology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:mouse· 3 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Ganesh Kosher· 2 shared Akash Gujaral· 1 shared Harsika Nahar· 1 shared Tinku Gupta· 1 shared

Activity by Year

2023-2023 · peak 4/yr

Co-Author Collaboration Network

4 top collaborators · 1 mutual co-author link

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2 shared papersCell Biology

Ganesh Kosher

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4 papers

Recent·Most cited

Cell BiologybioRxivPreprintAug 18, 2023

ABCB7 deficiency increases endoplasmic reticulum mitochondria coupling and mTOR independent autophagy flux in H9c2 cardiomyocytes

Shivanshu Chandan, Ganesh Kosher

This study shows ABCB7 deficiency increases ER-mitochondria coupling and mTOR-independent autophagy in H9c2 cells without altering cristae structure or causing cell death.

DOI 10.1101/2023.08.18.553927

mousebulk RNA-seq

𝕏 PostBluesky

Pharmacology & ToxicologybioRxivPreprintJul 28, 2023

Nepicastat, a dopamine-beta-hydroxylase inhibitor decreases blood pressure and induces the infiltration of macrophages and B cells in the heart of spontaneous hypertensive rats

Shivanshu Chandan, Ganesh Kosher

Nepicastat reduces systolic blood pressure and intraventricular septal thickness in SHR rats but increases macrophage and B cell infiltration in the heart.

DOI 10.1101/2023.07.28.549206

ratproteomics

𝕏 PostBluesky

Cell BiologybioRxivPreprintJun 11, 2023

Can elevated plasma Adiponectin and Ghrelin counteract inflammation in the aging heart?

Harsika Nahar, Shivanshu Chandan

The paper investigates how elevated plasma adiponectin and ghrelin levels may counteract inflammation in aging hearts by reducing inflammatory molecules like leptin.

DOI 10.1101/2023.06.11.544501

mousebulk RNA-seq

𝕏 PostBluesky

ImmunologybioRxivPreprintApr 28, 2023

Age-associated elevated inflammation and immune pathways in the mice heart are linked to Adiponectin-Adipor1-RelA signaling

Tinku Gupta, Akash Gujaral, Shivanshu Chandan

This study identifies age-related inflammation in mouse hearts linked to Adiponectin-Adipor1-RelA signaling through gene expression, protein analysis, and functional experiments.

DOI 10.1101/2023.04.28.538681

mousebulk RNA-seq

𝕏 PostBluesky