Author
Johns Hopkins UniversityPrimary ORCID profile (0000-0003-1818-0831 · 2 papers)Unclaimed ORCID profile · follow to get notified of new preprints
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
3 papers
Recent·Most cited
Shuangshuang Yang, Shuai Wu, Silian Chen…·Jenny P.‐Y. Ting
The paper shows that cGAS hyperactivates in response to unpaired DNA (Bu-DNA) by bending it into a V-shape, revealing a new activation mechanism.
Shuai Wu, Christina M Stallings, Stephanie Torres…·Jungsan Sohn
This study shows cGAS forms a protein-dsDNA mesh that enables dsDNA-specific and length-dependent activation through higher-order assembly.
Jacob Lueck, Alexander Strom, Stephanie Torres…·Jungsan Sohn
This study shows that cGAS dimerization on dsDNA forms gel-like condensates, which activate cGAS and protect dsDNA, while single-stranded RNA can dissolve these condensates.