ImmunologyScience AdvancesPeer-reviewed
Xenopus IgX informs engineering strategies of IgM and IgG hexamers
Ruixue Zhang, Chenggong Ji, Shuhan Li…·Junyu Xiao
The paper presents the cryo-EM structure of Xenopus IgX, revealing a hexameric assembly that informs strategies for engineering human IgM and IgG hexamers with therapeutic applications.