Cell BiologybioRxivPreprint
Continuous Large Maf Activity Maintains Fast Myofiber Identity and Multicellular Homeostasis in Adult Skeletal Muscle
DOI 10.64898/2026.10.09.758120
Author
Shunya Sadaki
University of Tsukuba
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
Biology Disciplines
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2024-2026 · peak 3/yrCo-Author Collaboration Network
10 top collaborators · 38 mutual co-author linksFocal author (center)Selected co-authorORCID co-authorUnlinked name
Curved chords = mutual co-authorship5 papers
Recent·Most cited
- Cell BiologybioRxivPreprint
Cardiac-Detargeted MyoAAV Enables Systemic Nrl-Mediated Fast Myofiber Remodeling and Hypertrophy Across Multiple Skeletal Muscles
Keisuke Hitachi, Shunya Sadaki, Masato Watanabe…·Ryo Fujita
This paper develops a modified MyoAAV vector that detargets cardiac expression, enabling safe systemic induction of fast myofiber remodeling and hypertrophy in skeletal muscles.
1 citation - PhysiologybioRxivPreprint
c-MAF transduces fast motor neuron firing to sustain fast-glycolytic myofibers and neuromuscular junctions
Edgar Jauliac, Stéphanie Backer, Shunya Sadaki…·Pascal Maire
This study identifies c-MAF as a mediator of motoneuron activity in maintaining fast-glycolytic muscle fibers and neuromuscular junctions through chromatin accessibility changes and gene regulation.
- Cell BiologySkeletal MusclePeer-reviewed
Large MAF Transcription Factors Reawaken Evolutionarily Dormant Fast-Glycolytic Type IIb Myofibers in Human Skeletal Muscle
Shunya Sadaki, Ryosuke Tsuji, Takuto Hayashi…·Ryo Fujita
This study identifies large MAF transcription factors as inducers of type IIb myofibers in humans, enhancing glycolytic capacity and correlating with power training.
16 citationstop 4% - Cell BiologyStem CellsPeer-reviewed
Dual-specificity phosphatases 13 and 27 as key switches in muscle stem cell transition from proliferation to differentiation
Takuto Hayashi, Shunya Sadaki, Ryosuke Tsuji…·Ryo Fujita
The paper identifies Dusp13 and Dusp27 as MYOD target genes that regulate muscle stem cell transition from proliferation to differentiation during myogenesis.
7 citations