Skyler Demis

This study investigates sex- and pathway-specific synaptic adaptations in mPFC-NAc circuits following remifentanil self-administration and abstinence, revealing differences in AMPA/NMDA ratios and presynaptic signaling.

This study shows that GIRK channel signaling in male mice is critical for prelimbic cortical function and stress-induced cognitive flexibility, but not in females.

This study investigates the role of parvalbumin interneuron GIRK signaling in affect and cognition in male and female mice, finding sex-specific effects on behavior and neuronal firing.

This study identifies sex-specific synaptic changes in the prefrontal cortex that underlie opioid-induced cognitive impairment and suggests sex-based interventions for addiction treatment.