Author
École Polytechnique Fédérale de Lausanne
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
6 papers
Recent·Most cited
Arpine Sokratian, Ye Zhou, Meltem Tatlı…·Andrew B. West
This study reports the atomic structure of mouse α-synuclein fibrils and shows they differ structurally and functionally from human fibrils linked to Parkinson's and MSA.
Sonia Donzelli, Sinéad A. O’Sullivan, Anne‐Laure Mahul‐Mellier…·Hilal Ahmed Lashuel
This study shows that nitration of alpha-synuclein after fibrillization reduces its seeding activity and pathology formation in neurons and in vivo.
Hilal Ahmed Lashuel, Anne‐Laure Mahul‐Mellier, Salvatore Novello…·Nicolas Guex
The paper shows that neighboring post-translational modifications affect the detection of phosphorylated alpha-synuclein at Serine 129 by existing antibodies.
Senthil T. Kumar, Anne‐Laure Mahul‐Mellier, Ramanath Narayana Hegde…·Hilal Ahmed Lashuel
The paper investigates the effects of the E83Q mutation on alpha-synuclein aggregation and toxicity, finding it accelerates fibrillization and enhances pathological features in neuronal models.
René L. Vidal, Denisse Sepúlveda, Paulina Troncoso-Escudero…·Claudio A. Hetz
This study shows that forcing dimerization between ATF6f and XBP1s enhances UPR activity, reducing protein aggregation in neurodegenerative disease models.
Senthil T. Kumar, Sonia Donzelli, Anass Chiki…·Hilal Ahmed Lashuel
This paper introduces a centrifugation-based filtration protocol to isolate and quantify α-synuclein monomers, oligomers, and fibrils to improve experimental reproducibility in Parkinson's research.