CRISPR/Cas9 genome editing to generate single variant Plasmodium falciparum lines and enable reverse genetic studies of PfEMP1 function in live parasites
Stanley E Otoboh, Hussein Molu Abkallo, Jessie Jungels…·J Alexandra Rowe
Author
University of Edinburgh
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
3 papers
Recent·Most cited
Stanley E Otoboh, Hussein Molu Abkallo, Jessie Jungels…·J Alexandra Rowe
Priscilla Ngotho, Kathleen D. Press, Megan Peedell…·Matthias Marti
This study shows that surface remodelling in Plasmodium falciparum gametocytes helps evade immune detection and facilitates transmission by controlling their sequestration and release into the bloodstream.
Florence McLean, Brian R. Omondi, Nouhoum Diallo…·J. Alexandra Rowe
The paper identifies novel PfEMP1 variants associated with rosetting in Plasmodium falciparum, expanding the known types of PfEMP1 that mediate this phenotype.