NeuroscienceScientific ReportsPeer-reviewed
Tauopathy in the APPswe/PS1ΔE9 mouse model of familial Alzheimer’s disease
Athanasios Metaxas, Camilla Thygesen, Stefan J. Kempf…·Bente R. Finsen
This study shows that tau pathology develops spontaneously in APPswe/PS1ΔE9 mice, demonstrating that amyloidosis is necessary and sufficient to drive tauopathy in familial AD models.
40 citationstop 5%