BiochemistrybioRxiv
Hepatitis C Virus Drugs Simeprevir and Grazoprevir Synergize with Remdesivir to Suppress SARS-CoV-2 Replication in Cell Culture
K. Bafna, K. White, B. Harish…·G. T. Montelione
This paper evaluates HCV protease inhibitors as potential SARS-CoV-2 antivirals, finding that simeprevir and grazoprevir synergize with remdesivir to enhance antiviral activity against SARS-CoV-2 in cell culture.
DOI 10.1016/j.celrep.2021.109133