Cell BiologybioRxiv
Cell adhesion molecule IGPR-1 activates AMPK connecting cell adhesion to energy sensing and autophagy
R. Amraei, T. Alwani, R. Ho…·N. Rahimi
This study shows IGPR-1 activates AMPK, linking cell adhesion to autophagy through phosphorylation of ULK1 and Beclin-1, and identifies IKKβ as a key kinase in this pathway.
DOI 10.1074/jbc.ra120.014790