Exaggerated in vivo IL-17 responses discriminate recall responses in active TB
G. Pollara, C. T. Turner, G. S. Tomlinson, L. C. Bell, A. Khan, L. F. Peralta, A. Folino, A. Akarca, C. Venturini, T. Baker, F. L. Ricciardolo, T. Marafioti, C. Ugarte-Gil, D. A. Moore, B. M. Chain, M. Noursadeghi
The paper shows that exaggerated IL-17A/F responses in active TB distinguish it from cured or latent TB, suggesting therapeutic targeting of this pathway.
bioRxiv · Jul 31, 2020Immunology