Pharmacology & ToxicologybioRxivPreprint
Acetylation of L-leucine switches its carrier from the L-amino acid transporter (LAT) to organic anion transporters (OAT)
G. C. Churchill, M. Strupp, T. Bremova-Ertl…·A. Galione
This paper shows that N-acetyl-L-leucine is transported by organic anion transporters (OAT) instead of LAT, explaining its drug-like properties compared to L-leucine.
DOI 10.1101/2020.11.12.379701