Author

T. Bub

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

P. H. Brigleb· 3 shared S. Schultz-Cherry· 3 shared V. A. Meliopoulos· 3 shared A. Vazquez-Pagan· 2 shared B. Sharp· 2 shared J. C. Crawford· 2 shared M. Smith· 2 shared S. Tan· 2 shared

Activity by Year

2023-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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3 shared papersMicrobiology

P. H. Brigleb

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Maternal immunization with distinct influenza vaccine platforms elicits unique antibody profiles that impact the protection of offspring

A. Vazquez-Pagan, E. K. Roubidoux, S. Cherry, B. Livingston, T. Bub, L. Lazure, B. Sharp, T. Confer, P. H. Brigleb, R. Honce, K. T. Whitt, M. Johnson, V. A. Meliopoulos, S. Schultz-Cherry

This study compares antibody profiles from maternal influenza vaccines in mice, showing LAIV and rHA provide better offspring protection than TIV.

bioRxiv · Oct 30, 2023 · PreprintMicrobiology

The beta 6 Integrin Negatively Regulates TLR7-Mediated Epithelial Immunity via Autophagy During Influenza A Virus Infection

M. Smith, V. A. Meliopoulos, S. Tan, T. Bub, P. H. Brigleb, B. Sharp, J. C. Crawford, M. S. Prater, S. M. Pruett-Miller, S. Schultz-Cherry

This study shows that beta 6 integrin suppresses TLR7-mediated epithelial immunity during influenza A virus infection by promoting autophagy and altering TLR7 trafficking.

bioRxiv · Aug 28, 2023 · PreprintImmunology

Astrovirus replication is dependent on induction of double membrane vesicles through a PI3K-dependent, LC3-independent pathway

T. Bub, V. Hargest, S. Tan, M. Smith, A. Vazquez-Pagan, T. Flerlage, P. H. Brigleb, V. A. Meliopoulos, B. D. Lindenbach, V. Cortez, J. C. Crawford, S. Schultz-Cherry

This study shows astrovirus replication depends on PI3K-dependent, LC3-independent DMV formation, suggesting PI3K as a therapeutic target for viral infections.

bioRxiv · Apr 11, 2023 · PreprintMicrobiology