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T. C. Shimko

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Biophysics· 1

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Assay:ChIP-seq· 1 Approach:deep learning· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Organism:yeast· 1

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A. K. Aditham· 1 shared A. M. Keys· 1 shared D. D. Le· 1 shared P. Fordyce· 1 shared Y. Orenstein· 1 shared

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1 shared paperBiophysics

A. K. Aditham

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1 paper

Recent·Most cited

BiophysicsbioRxivSep 26, 2017

Comprehensive, high-resolution binding energy landscapes reveal context dependencies of transcription factor binding

D. D. Le, T. C. Shimko, A. K. Aditham…·P. Fordyce

The paper measures TF-DNA binding energies for yeast TFs using a novel sequencing assay and finds that flanking mutations significantly affect binding energy, challenging current site definitions.

DOI 10.1073/pnas.1715888115

yeastDNA methylation

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